Extensions of linear models are very commonly used in the analysis of biological data. Whereas goodness of fit measures such as the coefficient of determination (R2) or the adjusted R2 are well established for linear models, it is not obvious how such measures should be defined for generalized linear and mixed models.
Dr Alex Whan (CSIRO) presents 'Repset: A Reproducible, Extensible and Portable Framework for Evaluating Computation Tools' and A/Professor Conrad Burden (MSI) discusses 'Sampling Distributions from a Neutral Multi-allele Wright-Fisher Diffusion with Applications to Estimating Mutation Rate Matrices'.
Rigor and reproducibility are at the core of modern science and set apart scientific inquiry from pseudoscience. Statistics, data science skills, and rigor are fundamental to excel in 21st century biology. In addition, these are highly sought-after skill-sets on the current job market.
Dr Adrià Closa (JCSMR) presents 'From Big Data to Translational Research in Paediatric Acute Leukaemia' and Dr Hawlader Al-Mamun (CSIRO, Data61) discusses 'Finding Treasure (Epistatic Interactions) In A Dark Random Forest'.
Dr Nasser Bagheri (RSPH) presents Visualising Health Care Ecosystem: From Biologic to Population Health Data to Inform Policy and Practice and Mr Renzo Balboa (NCIG) discusses Characterising the Diversity of Alu repeats in Humans